E-ISSN: 2822-2741
Localized Lymphoid Hyperplasia of the Colon Mimicking Lymphoma in a Patient with Ulcerative Colitis
1Department of Internal Medicine, Beaumont Health, Royal Oak, Michigan, USA
2Yeditepe University, School of Medicine, Istanbul, Türkiye
3Department of Pathology, Istanbul University, Istanbul School of Medicine, Istanbul, Türkiye
4Division of Gastroenterology and Hepatology, Istanbul University, Istanbul School of Medicine, Istanbul, Türkiye
Journal of Enterocolitis 2024; 3(1): 14-16 DOI: 10.14744/Jenterocolitis.2024.240668
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Localized lymphoid hyperplasia (LLH) of the colon is a rare clinical entity often considered benign, typically resolving without intervention. However, its endoscopic appearance may resemble colonic lymphoma, such as MALT-lymphoma or diffuse large B-cell lymphoma, underscoring the importance of histopathological evaluation for accurate diagnosis. Here, we present a case of a 54-year-old asymptomatic man with ulcerative colitis (UC) diagnosed with LLH of the rectum. While rectal bleeding is the most common presentation of LLH, patients can be asymptomatic. Although rare, colonic lymphoma has been reported in patients with UC. Clinicians should refrain from diagnosing lymphoma without histopathological confirmation and recognize the typically benign course of LLH in most cases.