Two Cases of Malignant Transformation in Crohn’s Disease with  Perianal Involvement

Dağcı, Gizem; Varel, Sibel; Büyük, Melek; Çavuş, Bilger; Çiftçibaşı Örmeci, Aslı; Akyüz, Filiz; Kaymakoğlu, Sabahattin

doi:10.14744/Jenterocolitis.2023.231457

Two Cases of Malignant Transformation in Crohn’s Disease with Perianal Involvement

Gizem Dağcı¹ ,

Sibel Varel² ,

Melek Büyük³ ,

Bilger Çavuş¹ ,

Aslı Çiftçibaşı Örmeci¹ ,

Filiz Akyüz¹ ,

Sabahattin Kaymakoğlu¹

¹Division of Gastroenterohepatology, Department of Internal Medicine, Istanbul University, Faculty of Medicine, İstanbul, Türkiye
²Department of Internal Medicine, Istanbul University, Faculty of Medicine, İstanbul, Türkiye
³Department of Pathology, Istanbul University, Faculty of Medicine, İstanbul, Türkiye

Journal of Enterocolitis 2023; 2(3): 66-68 DOI: 10.14744/Jenterocolitis.2023.231457

Full Text PDF

Abstract

This report includes 2 cases of Crohn’s disease with perianal involvement in which adenocarcinoma developed in the setting of a fistula. The cases illustrate the importance of considering the development of neoplasia in the presence of fistula, treatment-resistant symptoms, and rectal discharge.

Keywords: Crohn’s disease, malignancy, perianal disease