Abstract
Melanoma is a malignant tumor that arises from melanocytes that are usually located in the skin, retina, meninges, and the anus. Melanoma of the gastrointestinal tract represents 1%-3% of the gastrointestinal system, which is most likely a metastasis of a skin, ocular, or anal primary lesion. It is a common malignancy whose prevalence is increasing. Most of the time, the metastatic lesion was diagnosed during post-mortem, but fewer than 9% of melanoma patients are diagnosed with gastrointestinal involvement while living. Small intestinal melanoma metastasis is not easily diagnosed. In this study, we reported 2 cases of intestinal-associated malignant melanoma that was diagnosed via capsule endoscopy and double-balloon enteroscopy.